Botox on the Brain
Botox on the brain was detected by The Italian National Research Council’s Institute of Neurosciences after conducting a study whereby Botox was injected into muscles around the whiskers of rats. In fact, it only took days before Botox had migrated to brain stem cells and within six months the migration continued to other areas of the brain.
The study suggested that an ingredient in Botox inhibits nerve cell signals through the destruction of an essential protein that assists with cell interaction. By the same token, the amount of Botox used for cosmetic purposes is comparatively small.
In addition, doctors take special care during the injection to ensure it has a local effect. The risk that Botox will implicate the central nervous system in a cosmetic Botox patient has not been documented since it was approved by the FDA in 1989. Botox continues to be a mainstay for releasing contractions that create lines on the forehead and reducing the possibility of new wrinkles.
“We need further data in humans to demonstrate accuracy in the results that Botox travels and causes inhibition of nerve cell communication in order to substantiate the validity of this claim. Furthermore, the dissemination of high dosages of Botox into rats and the notation of by products in the brains of rats does not relate to humans. This study does not produce a cause for concern in Botox treatment. Botox is one of the safest treatments available for smoothing out wrinkles on the forehead.”, explains Dr. Stephen Greenberg of New York.
The use of Botox in humans for cosmetic purposes has produced complications in rare cases, including lack of movement in the treatment area and sagging eye lids. Botox is used in higher dosages for other medical applications. These medical applications include: muscle spasms in celebral palsy victims and migraine headaches. There have been reports of Botox complications resulting from higher dosages that include difficulty breathing and swallowing.
http://www.jneurosci.org/
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